The inevitable QSAR renaissance

Polychromy in Greek Sculpture

This strong prejudice was of course natural. Ever since the Renaissance, artists had produced white marble sculpture, in imitation, oddly enough, of the Greek and Roman examples known to them, which in the course of time had lost their coloring. It was not easy to give up a belief that had been held for generations and one that had, moreover, started a new practice; for previous to the Renaissa...

Examining the Relationship between “Science” and “Religion” in Socio-Cultural Context of the Renaissance: A Kuhnian Reading of Bacon’s New Atlantis

Thomas Kuhn’s model of paradigm shift as an intra-systemic framework to account for changes within the scientific discourse has been adopted by scholars in different fields as diverse as sociology, theology, economy, and education, to name only a few. The present study argues that the same model can usefully be drawn upon to examine the relationship between ‘science’ and ‘religion’ with some re...

Comparison of Different 2D and 3D-QSAR Methods on Activity Prediction of Histamine H3 Receptor Antagonists

     Histamine H3 receptor subtype has been the target of several recent drug development programs. Quantitative structure-activity relationship (QSAR) methods are used to predict the pharmaceutically relevant properties of drug candidates whenever it is applicable. The aim of this study was to compare the predictive powers of three different QSAR techniques, namely, multiple linear regression ...

Comparison of Different 2D and 3D-QSAR Methods on Activity Prediction of Histamine H3 Receptor Antagonists

     Histamine H3 receptor subtype has been the target of several recent drug development programs. Quantitative structure-activity relationship (QSAR) methods are used to predict the pharmaceutically relevant properties of drug candidates whenever it is applicable. The aim of this study was to compare the predictive powers of three different QSAR techniques, namely, multiple linear regression ...

A Review of the Contextual Adaptability of Three Contemporary Urban Paradigms: New Urbanism, Urban Village and Urban Renaissance